SCHEMBL2964853

SCHEMBL2964853

Cc1c(Br)c(Br)c2c(c1-c1ccccc1)[CH]c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2974272 0.83 TP53 (0.30) MAPK1
SCHEMBL2959180 0.76 ALDH1A1 (0.36) ALDH1A1MAPK1MEN1KMT2APDCD1
SCHEMBL2974304 0.69 ALDH1A1 (0.38) ALDH1A1MAPK1MEN1KMT2A
SCHEMBL2966124 0.69 GABRA1 (0.31)
SCHEMBL217878 0.68 ALDH1A1 (0.36) ALDH1A1MAPK1KMT2A
SCHEMBL2965679 0.68 ALDH1A1 (0.41) ALDH1A1MAPK1MEN1KMT2A
SCHEMBL2975317 0.68 GCGR (0.32)
SCHEMBL2872579 0.67 TSHR (0.32) ALDH1A1MEN1KMT2A
SCHEMBL2961344 0.67 KDM4E (0.34) ALDH1A1
SCHEMBL1029673 0.66 ALDH1A1 (0.41) ALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ALDH1A1 4332/4885MAPK1 3118/4885MEN1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.