SCHEMBL29648532

SCHEMBL29648532

COC(=O)CCC(=O)N[C@@H](CO)C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
MME P08473 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
TGFBR1 P36897 1/20 0.38
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.38
IMPDH2 P12268 1/20 0.38
IMPDH1 P20839 1/20 0.38
CYP2C9 P11712 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29530212 0.85 TGFBR1 (0.55) TSHRMMEL3MBTL1TGFBR1
SCHEMBL16086393 0.85 POLB (0.49) MMEKMT2APOLBHDAC1HDAC6
SCHEMBL29648540 0.82 BIRC2 (0.52) TSHRMMEPOLB
SCHEMBL1705845 0.79 HDAC6 (0.45) KMT2AHDAC1HDAC6
SCHEMBL13453175 0.79 MME (0.46) TSHRMMEL3MBTL1KMT2APOLB
SCHEMBL11940446 0.79 MME (0.46) TSHRMMEL3MBTL1KMT2APOLB
SCHEMBL20503303 0.77 KMT2A (0.56) KMT2AHDAC1HDAC6
SCHEMBL20503304 0.77 KMT2A (0.56) KMT2AHDAC1HDAC6
SCHEMBL13236359 0.77 KMT2A (0.50) TSHRL3MBTL1KMT2APOLB
SCHEMBL21606748 0.77 MME (0.40) MMETGFBR1CYP2C9HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4589059-A2 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION Personal Genome Diagnostics, Inc. (US) 2025-07-23 EP disclosed
EP-3717520-B1 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION PERSONAL GENOME DIAGNOSTICS INC (US) 2025-04-16 EP disclosed
US-20230160002-A1 Process for Microsatellite Instability Detection Personal Genome Diagnostics Inc. (US) 2023-05-25 US disclosed
US-11597967-B2 Process for microsatellite instability detection Personal Genome Diagnostics Inc. (US) 2023-03-07 US disclosed
US-20220389449-A1 COMPOSITIONS FOR THE TREATMENT OF DISEASE VOYAGER THERAPEUTICS, INC. 2022-12-08 US disclosed
US-11326182-B2 Compositions for the treatment of disease VOYAGER THERAPEUTICS, INC. (US) 2022-05-10 US disclosed