SCHEMBL29648540

SCHEMBL29648540

COC(=O)CCC(=O)N[C@@H](CC(C)C)C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 4/20 0.52
TAS1R3 Q7RTX0 7/20 0.51
TAS1R1 Q7RTX1 7/20 0.51
FOLH1 Q04609 1/20 0.48
MME P08473 1/20 0.48
POLB P06746 1/20 0.46
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27927721 0.90 FOLH1 (0.49) BIRC2TAS1R3TAS1R1FOLH1POLB
SCHEMBL30872978 0.86 FOLH1 (0.51) BIRC2TAS1R3TAS1R1FOLH1MME
SCHEMBL29638170 0.86 ALDH1A1 (0.55) FOLH1MMETSHR
SCHEMBL29648522 0.86 NPSR1 (0.46) BIRC2TAS1R3TAS1R1MMEPOLB
SCHEMBL27909770 0.86 TAS1R3 (0.54) BIRC2TAS1R3TAS1R1FOLH1MME
SCHEMBL27909811 0.86 TAS1R3 (0.54) BIRC2TAS1R3TAS1R1FOLH1MME
SCHEMBL4246400 0.86 TAS1R3 (0.54) BIRC2TAS1R3TAS1R1FOLH1MME
SCHEMBL26292321 0.84 TAS1R3 (0.53) BIRC2TAS1R3TAS1R1FOLH1MME
SCHEMBL29648532 0.82 TSHR (0.48) MMEPOLBTSHR
SCHEMBL4704329 0.81 TAS1R3 (0.50) BIRC2TAS1R3TAS1R1FOLH1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4589059-A2 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION Personal Genome Diagnostics, Inc. (US) 2025-07-23 EP disclosed
EP-3717520-B1 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION PERSONAL GENOME DIAGNOSTICS INC (US) 2025-04-16 EP disclosed
US-20240124889-A1 COMPOSITIONS AND METHODS FOR THE VECTORED AUGMENTATION OF PROTEIN DESTRUCTION, EXPRESSION AND/OR REGULATION VOYAGER THERAPEUTICS, INC. 2024-04-18 US disclosed
US-20230160002-A1 Process for Microsatellite Instability Detection Personal Genome Diagnostics Inc. (US) 2023-05-25 US disclosed
US-11597967-B2 Process for microsatellite instability detection Personal Genome Diagnostics Inc. (US) 2023-03-07 US disclosed
US-20220389449-A1 COMPOSITIONS FOR THE TREATMENT OF DISEASE VOYAGER THERAPEUTICS, INC. 2022-12-08 US disclosed
US-11326182-B2 Compositions for the treatment of disease VOYAGER THERAPEUTICS, INC. (US) 2022-05-10 US disclosed