Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | APOL1 | O14791 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987871 | 1.00 | ADORA2A (0.41) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL29648759 | 0.92 | KDM4E (0.39) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL22979344 | 0.92 | KDM4E (0.39) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL29648840 | 0.90 | ADORA2A (0.41) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL22979154 | 0.90 | ADORA2A (0.41) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL29648598 | 0.89 | ALDH1A1 (0.41) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL22979277 | 0.89 | ALDH1A1 (0.41) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL22980234 | 0.88 | ADORA1 (0.40) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL29648555 | 0.88 | ADORA1 (0.40) | ADORA2AADORA1ADORA3MKNK1MKNK2 | |
| SCHEMBL22979466 | 0.88 | ADORA3 (0.37) | ADORA2AADORA1ADORA3FPR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |