Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988389 | 1.00 | KDM4E (0.36) | KDM4EHPGDSROCK2ALDH1A1PROKR1 | |
| SCHEMBL22980060 | 1.00 | KDM4E (0.36) | KDM4EHPGDSROCK2ALDH1A1PROKR1 | |
| SCHEMBL22979251 | 0.91 | KDM4E (0.36) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL29648654 | 0.91 | KDM4E (0.36) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL22981097 | 0.91 | KDM4E (0.36) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL29648603 | 0.91 | KDM4E (0.36) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL22979931 | 0.88 | THRB (0.40) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL22979389 | 0.88 | THRB (0.40) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL29648684 | 0.88 | THRB (0.40) | KDM4EHPGDSALDH1A1ZAP70SYK | |
| SCHEMBL29648778 | 0.88 | THRB (0.40) | KDM4EHPGDSALDH1A1ZAP70SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |