Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979389 | 1.00 | THRB (0.40) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL29648778 | 1.00 | THRB (0.40) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL22979931 | 1.00 | THRB (0.40) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL29648713 | 0.90 | THRB (0.39) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL22979543 | 0.90 | THRB (0.39) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL29648589 | 0.90 | THRB (0.39) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL22988349 | 0.90 | THRB (0.39) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL22981005 | 0.90 | THRB (0.41) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL29648645 | 0.90 | THRB (0.41) | THRBMAPTRXFP1HPGDSSMN1; SMN2 | |
| SCHEMBL22979080 | 0.89 | MAPT (0.42) | THRBMAPTRXFP1HPGDSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |