Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988349 | 1.00 | THRB (0.39) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL29648589 | 1.00 | THRB (0.39) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL22979543 | 1.00 | THRB (0.39) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL29648778 | 0.90 | THRB (0.40) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL29648684 | 0.90 | THRB (0.40) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL22979931 | 0.90 | THRB (0.40) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL22979389 | 0.90 | THRB (0.40) | THRBRXFP1MAPTHPGDSSMN1; SMN2 | |
| SCHEMBL29648679 | 0.90 | MKNK1 (0.36) | THRBMAPTSMN1; SMN2KDM4EMKNK1 | |
| SCHEMBL22979159 | 0.90 | MKNK1 (0.36) | THRBMAPTSMN1; SMN2KDM4EMKNK1 | |
| SCHEMBL22979537 | 0.90 | MCHR1 (0.39) | MKNK1MKNK2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |