SCHEMBL2964872

SCHEMBL2964872

CC1=Cc2ccc(Br)c(-c3ccccc3C)c2C1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 2/20 0.30
CASP3 P42574 2/20 0.30
RAB9A P51151 2/20 0.30
SENP8 Q96LD8 2/20 0.30
SENP7 Q9BQF6 2/20 0.30
SENP6 Q9GZR1 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2975911 0.89
SCHEMBL2963346 0.84 DHFR (0.38) ALDH1A1HTTSMN1; SMN2
SCHEMBL2962017 0.82 PTGS1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL2961338 0.81 BRD4 (0.32) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL2972127 0.80 NR1H2 (0.31)
SCHEMBL2964859 0.77
SCHEMBL29776193 0.76 BRD4 (0.35) ALDH1A1MEN1KMT2ANPC1CASP3
SCHEMBL2964871 0.75 ALDH1A1 (0.30) ALDH1A1
SCHEMBL2959376 0.75 GRIA1 (0.35) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL2974370 0.74 ALDH1A1 (0.35) ALDH1A1NPC1CASP3RAB9ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ALDH1A1 4332/4885MEN1 750/4885POLB 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.