SCHEMBL29648901

SCHEMBL29648901

Cc1cc(Br)cc(Cl)c1N=C=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 2/20 0.34
TRPA1 O75762 1/20 0.34
NMT1 P30419 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17027567 1.00 GABRA1 (0.36) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL6330610 0.86 MAPK1 (0.42) GABRA1GABRB2MAPK1TDP1NMT1
SCHEMBL1457513 0.86 CYP3A4 (0.39) GABRA1GABRB2CYP3A4TRPA1
SCHEMBL3839590 0.85 GABRA1 (0.38) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL30438750 0.85 GABRA1 (0.38) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL10614885 0.79 GABRA1 (0.50) GABRA1GABRB2MAPK1TDP1NMT1
SCHEMBL11322087 0.78 GABRA1 (0.42) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL28566672 0.78 GABRA1 (0.36) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL17907296 0.76 GABRA1 (0.47) GABRA1GABRB2CYP3A4TRPA1
SCHEMBL10614836 0.75 POLB (0.38) GABRA1GABRB2MAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
EP-3997149-A1 POLYMERIZABLE COMPOSITIONS FOR PREPARING POLYISOCYANURATE-BASED PLASTICS HAVING EXTENDED WORKLIFE Covestro Intellectual Property GmbH & Co. KG (DE) 2022-05-18 EP disclosed