SCHEMBL30438750

SCHEMBL30438750

Cc1cc(C)c(N=C=O)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 2/20 0.36
TRPA1 O75762 1/20 0.36
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RAPGEF4 Q8WZA2 5/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839590 1.00 GABRA1 (0.38) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL11322087 0.90 GABRA1 (0.42) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL1192169 0.85 CYP3A4 (0.42) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL29648901 0.85 GABRA1 (0.36) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL17027567 0.85 GABRA1 (0.36) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL11428515 0.83 RAPGEF4 (0.34) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL3657241 0.82 CYP3A4 (0.39) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL28566672 0.81 GABRA1 (0.36) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL10614836 0.78 POLB (0.38) GABRA1GABRB2MAPK1TDP1CYP3A4
SCHEMBL2172972 0.78 CYP3A4 (0.46) GABRA1GABRB2TDP1CYP3A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
CN-112020525-B Adducts of amine catalysts for preparing isocyanurate polymers 科思创知识产权两合公司 2023-05-16 CN disclosed