Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988039 | 1.00 | MMP9 (0.39) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22979796 | 1.00 | MMP9 (0.39) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22988038 | 0.94 | MAPT (0.42) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22988040 | 0.93 | MMP9 (0.39) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22988056 | 0.93 | MMP9 (0.38) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL25118861 | 0.93 | MMP9 (0.38) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22987530 | 0.93 | MMP9 (0.40) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22987677 | 0.92 | MMP9 (0.38) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL22979870 | 0.91 | MAPT (0.48) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL29646384 | 0.91 | MAPT (0.48) | MMP9MMP1MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |