Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31058600 | 0.98 | ALDH1A1 (0.33) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL7479331 | 0.97 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL30995058 | 0.84 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL7953954 | 0.67 | — | — | |
| SCHEMBL4309011 | 0.64 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642871 | 0.62 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642898 | 0.60 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL31377549 | 0.59 | — | — | |
| SCHEMBL10638515 | 0.58 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10363679 | 0.58 | CRBN (0.33) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119522227-A | Macrocyclic compounds, pharmaceutical compositions and uses thereof | 贝达药业股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| WO-2024017358-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 贝达药业股份有限公司 | 2024-01-25 | — | — | WO | claimed |
| CN-119522227-A | Macrocyclic compounds, pharmaceutical compositions and uses thereof | 贝达药业股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-113527335-B | Macrocyclic compound as EGFR inhibitor and application thereof | 南京圣和药业股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-118488958-A | Compounds for degrading EGFR kinase | 百济神州有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2024017358-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 贝达药业股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| WO-2022135432-A1 | MACROCYCLIC HETEROCYCLIC COMPOUNDS AS EGFR INHIBITORS, AND USE THEREOF | 南京圣和药业股份有限公司 | 2022-06-30 | — | — | WO | disclosed |
| WO-2022117051-A1 | MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2022-06-09 | — | — | WO | disclosed |