SCHEMBL2964973

SCHEMBL2964973

CCCCC1=Cc2cc(Br)ccc2C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
NPC1 O15118 2/20 0.34
NFKB1 P19838 2/20 0.34
RAB9A P51151 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 1/20 0.34
PNMT P11086 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CHEK2 O96017 1/20 0.30
ROS1 P08922 1/20 0.30
MARK3 P27448 1/20 0.30
LTK P29376 1/20 0.30
FLT4 P35916 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2969428 0.95 TRPA1 (0.35) TRPA1NPC1NFKB1RAB9ANFKB2
SCHEMBL2974889 0.94 TRPA1 (0.34) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2970635 0.94 TRPA1 (0.34) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2974541 0.94 TRPA1 (0.34) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2971444 0.94 TRPA1 (0.34) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2969538 0.94 TRPA1 (0.34) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2974941 0.90 TRPA1 (0.37) TRPA1PNMTADRA2AADRA2BADRA2C
SCHEMBL2971828 0.87 NPC1 (0.34) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL2964680 0.83 TRPA1 (0.39) TRPA1NFKB1SMN1; SMN2PNMTADRA2A
SCHEMBL2964529 0.83 ADRA2A (0.33) NPC1NFKB1RAB9ANFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024134973-A1 COMPOUND, AND LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE AND ANTENNA EACH USING SAME DIC株式会社 2024-06-27 WO disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed