Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP8B1 | Q9UNU6 | 13/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134930 | 0.85 | CYP8B1 (0.54) | CYP8B1DPP4DPP8FAPP2RX7 | |
| SCHEMBL29650119 | 0.84 | CYP8B1 (0.49) | CYP8B1DPP4DPP8FAPP2RX7 | |
| SCHEMBL29649992 | 0.83 | DPP4 (0.42) | CYP8B1DPP4DPP8P2RX7 | |
| SCHEMBL5231477 | 0.77 | TACR3 (0.46) | DPP4DPP8P2RX7 | |
| SCHEMBL19877142 | 0.76 | HPGD (0.54) | CYP8B1 | |
| SCHEMBL22952373 | 0.76 | P2RX7 (0.48) | CYP8B1DPP4P2RX7 | |
| SCHEMBL23967596 | 0.75 | CYP8B1 (0.65) | CYP8B1 | |
| SCHEMBL19877063 | 0.75 | CYP8B1 (0.65) | CYP8B1 | |
| SCHEMBL19878066 | 0.75 | CYP8B1 (0.65) | CYP8B1 | |
| SCHEMBL19877064 | 0.75 | CYP8B1 (0.65) | CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255900-A2 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022118016-A2 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-06-09 | — | — | WO | disclosed |