SCHEMBL29650430

SCHEMBL29650430

Cc1nc2cnc(N3CCN(C)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(=O)O)csc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EIF4EBP1 Q13541 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29650523 0.94 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650419 0.93 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL28704403 0.92 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650561 0.90 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650447 0.88 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL22866598 0.85 EIF4EBP1 (0.86) EIF4EBP1
SCHEMBL28721906 0.85 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650631 0.84 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29560111 0.84 EIF4EBP1 (0.86) EIF4EBP1
SCHEMBL29650496 0.84 EIF4EBP1 (1.00) EIF4EBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3993875-A1 METHODS OF TREATING BRAF-MUTATED CANCER CELLS EFFECTOR THERAPEUTICS, INC. (US) 2022-05-11 — — EP disclosed
Send feedback