Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417832 | 0.81 | APP (0.58) | VKORC1APPMAPTKMT2AMEN1 | |
| SCHEMBL29884371 | 0.75 | APP (0.51) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL29035311 | 0.74 | KMT2A (0.66) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL30366382 | 0.74 | KMT2A (0.66) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL27160317 | 0.73 | APP (0.63) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL27414830 | 0.73 | APP (0.63) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL27160318 | 0.73 | APP (0.63) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL27160316 | 0.73 | APP (0.63) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL10603080 | 0.72 | APP (0.62) | APPMAPTKMT2AMEN1PNLIP | |
| SCHEMBL5309688 | 0.71 | VKORC1 (1.00) | VKORC1KMT2AMEN1PTPN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150006-B | Pyran compound and synthetic method thereof | 五邑大学 | 2022-07-05 | — | — | CN | disclosed |