Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | PNLIP | P16233 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035311 | 1.00 | KMT2A (0.66) | KMT2AMAPTMEN1PNLIPHSD17B10 | |
| Mahanimbine SCHEMBL18488203 | 0.79 | MAPT (1.00) | KMT2AMAPTMEN1PNLIPGAA | |
| Mahanimbine SCHEMBL2991765 | 0.79 | MAPT (1.00) | KMT2AMAPTMEN1PNLIPGAA | |
| Mahanimbine SCHEMBL18488200 | 0.79 | MAPT (1.00) | KMT2AMAPTMEN1PNLIPGAA | |
| Flindersine SCHEMBL3125149 | 0.76 | HSD17B10 (1.00) | KMT2AMAPTMEN1HSD17B10POLB | |
| SCHEMBL29651335 | 0.74 | VKORC1 (0.54) | KMT2AMAPTMEN1PNLIPGAA | |
| SCHEMBL28992256 | 0.73 | APP (0.55) | KMT2AMAPTMEN1PNLIPGAA | |
| SCHEMBL27417832 | 0.72 | APP (0.58) | KMT2AMAPTMEN1PNLIPGAA | |
| SCHEMBL30106809 | 0.70 | ALOX5 (0.53) | KMT2AMAPTMEN1PNLIPGAA | |
| SCHEMBL27191000 | 0.70 | ALOX5 (0.53) | KMT2AMAPTMEN1PNLIPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | claimed |
| CN-116036083-A | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-05-02 | — | — | CN | claimed |
| CN-116036083-B | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-116036083-A | Application of pyranoquinolinone compounds in preparation of medicines for treating cervical cancer | 江西省林业科学院 | 2023-05-02 | — | — | CN | disclosed |