SCHEMBL29652165

SCHEMBL29652165

CCCN(CCCS(=O)(=O)O)c1ccc(N=Nc2ccc(C#N)cn2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 13/20 0.47
▸ RIOK2 Q9BVS4 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ GAA P10253 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ POLB P06746 1/20 0.32
▸ HIF1A Q16665 1/20 0.31
▸ CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652167 0.87 KCNH2 (0.50) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL29652162 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL29652166 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL1057997 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL30767146 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL29652161 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL3424094 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL27033210 0.86 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL3173642 0.85 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1GAA
SCHEMBL4207580 0.85 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4244385-B1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MULTIPLEXDX S R O (SK) 2025-01-01 — — EP disclosed
US-20240026435-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2024-01-25 — — US disclosed
CN-116802315-A Loop-mediated isothermal nucleic acid amplification (LAMP) using LNA modified primers and metal-based colorimetric detection of amplified products 马尔提普莱克斯公司 2023-09-22 — — CN disclosed
EP-4244385-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2023-09-20 — — EP disclosed
WO-2022101259-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2022-05-19 — — WO disclosed
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