SCHEMBL29652373

SCHEMBL29652373

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3cc(Br)ccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.39
▸ BRD4 O60885 9/20 0.38
▸ KAT7 O95251 3/20 0.37
▸ KAT6A Q92794 3/20 0.37
▸ KAT6B Q8WYB5 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ TP53 P04637 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ KAT5 Q92993 1/20 0.34
▸ KAT8 Q9H7Z6 1/20 0.34
▸ POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652370 0.94 KAT7 (0.41) BRD4KAT7KAT6AKAT6BTP53
SCHEMBL21596810 0.93 TSHR (0.39) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL30838424 0.93 TSHR (0.39) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL28514884 0.91 BRD4 (0.38) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL29652474 0.91 BRD4 (0.38) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL31605548 0.86 MAPT (0.37) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL21596794 0.86 MAPT (0.37) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL21596842 0.85 KAT7 (0.36) TSHRBRD4KAT7KAT6AKAT6B
SCHEMBL21596783 0.85 KAT7 (0.36) BRD4KAT7KAT6AKAT6BTP53
SCHEMBL31605563 0.85 KAT7 (0.36) TSHRBRD4KAT7KAT6AKAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 TSHR 3584/4885BRD4 1909/4885KAT7 490/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B TSHR 832/4885BRD4 343/4885KAT7 271/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 TSHR 3583/4885BRD4 1913/4885KAT7 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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