SCHEMBL29652385

SCHEMBL29652385

Cc1nnc(-c2cccc(S(=O)(=O)Nc3noc4ccccc34)c2)o1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.57
HPGD P15428 3/20 0.53
NPSR1 Q6W5P4 3/20 0.53
TSHR P16473 2/20 0.53
MAPK1 P28482 2/20 0.53
ALOX15 P16050 1/20 0.53
ALDH1A1 P00352 4/20 0.47
HTT P42858 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 1/20 0.47
CCR9 P51686 1/20 0.47
CCKBR P32239 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
KAT6A Q92794 1/20 0.44
EDNRB P24530 3/20 0.44
EDNRA P25101 3/20 0.44
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609229 1.00 KMT2A (0.57) KMT2AHPGDNPSR1TSHRMAPK1
SCHEMBL29652523 0.83 KMT2A (0.61) KMT2ATSHRMAPK1KAT6AEDNRB
SCHEMBL21609230 0.83 KMT2A (0.61) KMT2ATSHRMAPK1KAT6AEDNRB
SCHEMBL24429767 0.82 KMT2A (0.56) KMT2AHPGDNPSR1TSHRMAPK1
SCHEMBL29603162 0.76 HPGD (0.56) HPGDNPSR1TSHRMAPK1ALOX15
SCHEMBL28724738 0.76 KMT2A (0.64) KMT2ANPSR1LMNACA1CA2
SCHEMBL21641913 0.75 KMT2A (0.61) KMT2AMAPK1MAPTKAT6AEPHX2
SCHEMBL29652542 0.75 KMT2A (0.61) KMT2AMAPK1MAPTKAT6AEPHX2
SCHEMBL21641925 0.74 KMT2A (0.66) KMT2AHPGDTSHRALDH1A1LMNA
SCHEMBL29652512 0.74 KMT2A (0.66) KMT2AHPGDTSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KMT2A 4165/4885HPGD 753/4885NPSR1 402/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KMT2A 890/4885HPGD 4289/4885NPSR1 1018/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KMT2A 4165/4885HPGD 752/4885NPSR1 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.