SCHEMBL2965249

SCHEMBL2965249

Brc1cc2c(cc1-c1cccs1)CC=C2

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
NPC1 O15118 1/20 0.31
ATM Q13315 1/20 0.31
LTK P29376 1/20 0.31
CDK5 Q00535 1/20 0.31
MST1R Q04912 1/20 0.31
DYRK1A Q13627 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2974834 0.94 MAOB (0.33) MAOBRAB9AKDM4EMAPTPPARG
SCHEMBL28996620 0.76 KDM4E (0.43) MAOBRAB9AKDM4EMAPTPPARG
SCHEMBL2965389 0.76
SCHEMBL2965315 0.74 ALDH1A1 (0.39)
SCHEMBL21694404 0.73 KCNH2 (0.46) KDM4EMAPT
SCHEMBL2975205 0.73 RAB9A (0.35) MAOBRAB9AKDM4EMAPTPPARG
SCHEMBL2968084 0.73 KDM4E (0.35) MAOBRAB9AKDM4EMAPTPPARG
SCHEMBL2963917 0.72 LTK (0.36) MAOBKDM4EMAPTTDP1LTK
SCHEMBL2970582 0.71 LTK (0.32) MAOBKDM4EMAPTTDP1LTK
SCHEMBL2967533 0.70 KCNH2 (0.36) RAB9AKDM4EMAPTPPARGNCOA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MAOB 902/4885RAB9A 1848/4885KDM4E 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.