Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23513893 | 1.00 | ILK (0.46) | ILKCSNK2A1TLR8TLR7TOP2A | |
| SCHEMBL23513929 | 0.79 | PIK3CG (0.45) | ILKCSNK2A1TLR8TLR7TOP2A | |
| SCHEMBL29653649 | 0.77 | KCNH2 (0.43) | ILKPIK3CGKCNH2 | |
| SCHEMBL23514151 | 0.77 | KCNH2 (0.43) | ILKPIK3CGKCNH2 | |
| SCHEMBL23513867 | 0.76 | APP (0.50) | TLR8TLR7 | |
| SCHEMBL29653626 | 0.76 | APP (0.50) | TLR8TLR7 | |
| SCHEMBL23500421 | 0.74 | ILK (0.40) | ILKCSNK2A1TLR8TLR7KDM4E | |
| SCHEMBL29653636 | 0.73 | TLR7 (0.45) | ILKTLR8TLR7TSHRLMNA | |
| SCHEMBL23514158 | 0.73 | TLR7 (0.45) | ILKTLR8TLR7TSHRLMNA | |
| SCHEMBL29653647 | 0.73 | CSNK2A1 (0.48) | CSNK2A1TOP2AHSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555565-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-114555565-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |