Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.45 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23514158 | 1.00 | TLR7 (0.45) | TLR7TLR8ILKNCF1APP | |
| SCHEMBL23513867 | 0.85 | APP (0.50) | TLR7TLR8APP | |
| SCHEMBL29653626 | 0.85 | APP (0.50) | TLR7TLR8APP | |
| SCHEMBL23500421 | 0.80 | ILK (0.40) | TLR7TLR8ILKAPPLMNA | |
| SCHEMBL29653716 | 0.80 | NUDT1 (0.33) | APP | |
| SCHEMBL29653633 | 0.80 | PRKCI (0.34) | APP | |
| SCHEMBL23513933 | 0.80 | NUDT1 (0.33) | APP | |
| SCHEMBL23513935 | 0.80 | PRKCI (0.34) | APP | |
| SCHEMBL23514066 | 0.80 | TLR8 (0.34) | TLR7TLR8APPCYP2D6 | |
| SCHEMBL29653671 | 0.80 | TLR8 (0.34) | TLR7TLR8APPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555565-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |