Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698927 | 1.00 | APP (0.34) | APPMAPTKDM4ELMNAMMP14 | |
| SCHEMBL29012247 | 1.00 | APP (0.34) | APPMAPTKDM4ELMNAMMP14 | |
| SCHEMBL14434778 | 0.83 | APP (0.39) | APPMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL9812776 | 0.83 | RELA (0.45) | APPMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL13138317 | 0.83 | RELA (0.45) | APPMAPTKDM4EMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11791882 | 0.82 | RELA (0.44) | APPMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL1226876 | 0.81 | APP (0.42) | APPMAPTKDM4EMAPK1TP53 | |
| SCHEMBL1226875 | 0.81 | APP (0.42) | APPMAPTKDM4EMAPK1TP53 | |
| SCHEMBL1226877 | 0.81 | APP (0.42) | APPMAPTKDM4EMAPK1TP53 | |
| Bromide SCHEMBL1227486 | 0.80 | APP (0.41) | APPMAPTKDM4EMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114441467-A | Dual-mode probe and application thereof | 山东大学 | 2022-05-06 | — | — | CN | disclosed |