Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754168 | 0.94 | CYP11B2 (0.48) | CKS1BSKP1SKP2CYP11B2MAP4K4 | |
| SCHEMBL15141123 | 0.91 | CKS1B (0.57) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL24753736 | 0.83 | CYP11B2 (0.48) | CKS1BSKP1SKP2CYP11B2MAP4K4 | |
| SCHEMBL1780700 | 0.82 | RET (0.51) | CKS1BSKP1SKP2CYP11B2MAP4K4 | |
| SCHEMBL29455974 | 0.82 | RET (0.51) | CKS1BSKP1SKP2CYP11B2MAP4K4 | |
| SCHEMBL31548343 | 0.81 | NAMPT (0.44) | GPR119ACACBNAMPT | |
| SCHEMBL31548144 | 0.78 | USP1 (0.40) | MAP4K4GPR119BACE1NAMPT | |
| SCHEMBL3085473 | 0.78 | BACE1 (0.42) | CKS1BSKP1SKP2MAP4K4BACE1 | |
| SCHEMBL29197468 | 0.77 | EED (0.42) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL24753077 | 0.76 | CKS1B (0.48) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605391-A | Quinoxaline derivative and preparation method and application thereof | 广州六顺生物科技股份有限公司 | 2022-06-10 | — | — | CN | disclosed |