Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4B | O94953 | 2/20 | 0.51 |
| ▸ | KDM5C | P41229 | 2/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654059 | 0.82 | KDM4B (0.51) | KDM4BKDM5CKDM5BKDM6BKDM4A | |
| SCHEMBL29654020 | 0.76 | CYP19A1 (0.65) | CYP1A1CYP1A2CYP1B1CYP19A1KDM4E | |
| SCHEMBL29654042 | 0.76 | KDM4E (0.57) | CYP1A1CYP1A2CYP1B1CYP19A1KDM4E | |
| SCHEMBL29654150 | 0.74 | CYP1A1 (0.49) | CYP1A1CYP1A2CYP1B1CYP19A1KDM4E | |
| SCHEMBL2486428 | 0.72 | CCR1 (0.61) | KDM4BKDM5CKDM5BKDM6BKDM4A | |
| SCHEMBL827247 | 0.72 | CCR1 (0.48) | CYP1A1CYP1A2CYP1B1KDM4EALDH1A1 | |
| SCHEMBL29653987 | 0.71 | MPL (0.56) | KDM4EALDH1A1LTA4HRAB9AMAPK1 | |
| SCHEMBL29654117 | 0.70 | ALDH1A1 (0.44) | CYP1A1CYP1A2CYP1B1KDM4EALDH1A1 | |
| SCHEMBL2624149 | 0.70 | TYK2 (0.39) | CYP1A1CYP1A2CYP1B1CYP19A1KDM4E | |
| SCHEMBL27745484 | 0.69 | ALDH1A1 (0.53) | KDM4BKDM5CKDM5BKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |