Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4B | O94953 | 2/20 | 0.51 |
| ▸ | KDM5C | P41229 | 2/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29653994 | 0.82 | KDM4B (0.51) | KDM4BKDM5CKDM5BKDM6BKDM4A | |
| SCHEMBL29654203 | 0.76 | KDM4E (0.85) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29654093 | 0.76 | MPL (0.58) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29653953 | 0.74 | ALDH1A1 (0.83) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29654053 | 0.74 | HSD17B10 (0.53) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15668883 | 0.73 | PDE10A (0.58) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2486428 | 0.72 | CCR1 (0.61) | KDM4BKDM5CKDM5BKDM6BKDM4A | |
| SCHEMBL21484712 | 0.72 | MPL (0.57) | KDM4BKDM5CKDM5BKDM6BKDM4A | |
| SCHEMBL31484870 | 0.72 | CCR1 (0.48) | KDM4ECYP1A2KDM4CGRM5 | |
| SCHEMBL810938 | 0.72 | CCR1 (0.48) | KDM4ECYP1A2KDM4CGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |