Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | NRP1 | O14786 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 3/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424957 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL30260039 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL30260098 | 0.72 | KRAS (0.38) | — | |
| SCHEMBL24778050 | 0.70 | L3MBTL1 (0.33) | — | |
| SCHEMBL24424954 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL25165297 | 0.66 | — | — | |
| SCHEMBL1624062 | 0.65 | IKBKB (0.46) | TLR9TLR8TLR7IKBKB | |
| SCHEMBL19716496 | 0.64 | NSD2 (0.44) | — | |
| SCHEMBL19924521 | 0.64 | ALDH1A1 (0.45) | IKBKB | |
| SCHEMBL29654166 | 0.64 | KRAS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022095960-A1 | KRAS INHIBITORS FOR TREATMENT OF CANCERS | 泰励生物科技（上海）有限公司 | 2022-05-12 | — | — | WO | disclosed |