Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25486721 | 1.00 | ABL1 (0.44) | ABL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL25486723 | 0.88 | ABL1 (0.44) | ABL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29654471 | 0.85 | ABL1 (0.44) | ABL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24524870 | 0.85 | ABL1 (0.44) | ABL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29476351 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL23540576 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL29476129 | 0.84 | SLC6A4 (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL23539775 | 0.84 | SLC6A4 (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24525035 | 0.82 | CFTR (0.50) | ABL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29654654 | 0.82 | CFTR (0.50) | ABL1ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133345-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2022-06-23 | — | — | WO | disclosed |