Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540246 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL2271964 | 0.85 | TTR (0.46) | KDM4EALDH1A1HSD17B10HPGDCFTR | |
| SCHEMBL145982 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL21857075 | 0.84 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL1035480 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL12394324 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| Hydrochloric Acid SCHEMBL7729822 | 0.82 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL19140760 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL410760 | 0.82 | CA1 (0.69) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL23539857 | 0.81 | ABL1 (0.55) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133345-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2022-06-23 | — | — | WO | disclosed |