Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11901648 | 0.83 | S100A4 (0.50) | S100A4PTPRCMAPTKMT2APDE7A | |
| SCHEMBL31713028 | 0.81 | S100A4 (0.45) | S100A4PTPRCMAPTKMT2APDE7A | |
| SCHEMBL26164138 | 0.81 | PDE7A (0.46) | S100A4PTPRCMAPTKMT2APDE7A | |
| SCHEMBL29565972 | 0.81 | PDE7A (0.46) | S100A4PTPRCMAPTKMT2APDE7A | |
| SCHEMBL214194 | 0.79 | TDP1 (0.50) | S100A4MAPTKMT2APDE7ASMN1; SMN2 | |
| SCHEMBL12479506 | 0.78 | TDP1 (0.48) | S100A4PTPRCMAPTKMT2ARECQL | |
| SCHEMBL26164167 | 0.76 | HSD17B10 (0.46) | S100A4PTPRCMAPTKMT2APDE7A | |
| SCHEMBL307855 | 0.75 | TDP1 (0.54) | S100A4PTPRCMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29355089 | 0.75 | TDP1 (0.54) | S100A4PTPRCMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15380368 | 0.75 | S100A4 (0.56) | S100A4PTPRCMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843874-B | Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer | 加利福尼亚大学董事会 | 2022-05-27 | — | — | CN | disclosed |