SCHEMBL214194

SCHEMBL214194

Nc1cccc([N+](=O)[O-])c1F

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PDE7A Q13946 1/20 0.50
GPR35 Q9HC97 2/20 0.48
TSHR P16473 4/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
GAA P10253 1/20 0.43
S100A4 P26447 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HSPB1 P04792 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3010961 0.84 TDP1 (0.61) TDP1SMN1; SMN2GPR35TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL28763100 0.82 TDP1 (0.58) TDP1SMN1; SMN2GPR35TSHRALDH1A1
SCHEMBL26164138 0.82 PDE7A (0.46) TDP1SMN1; SMN2PDE7AGPR35ALDH1A1
SCHEMBL29565972 0.82 PDE7A (0.46) TDP1SMN1; SMN2PDE7AGPR35ALDH1A1
SCHEMBL4063467 0.81 ALDH1A1 (0.50) TDP1SMN1; SMN2PDE7AGPR35TSHR
Valine SCHEMBL10510465 0.81 SLC7A5 (0.41) TDP1SMN1; SMN2PDE7AGPR35TSHR
SCHEMBL31713028 0.79 S100A4 (0.45) TDP1SMN1; SMN2PDE7AGPR35ALDH1A1
SCHEMBL29655222 0.79 S100A4 (0.45) TDP1SMN1; SMN2PDE7AGPR35ALDH1A1
SCHEMBL24548 0.78 TDP1 (0.60) TDP1SMN1; SMN2PDE7AGPR35TSHR
SCHEMBL307855 0.78 TDP1 (0.54) TDP1SMN1; SMN2GPR35TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043967-A1 PREPARATION METHOD FOR AND USE OF NANOPOROUS CARBON MATERIAL HAVING CONTINUOUS STRUCTURE 东南大学 2025-03-06 WO claimed
CN-118515261-A Preparation method of nano porous carbon material with continuous structure and application of nano porous carbon material as heat insulation material 东南大学 2024-08-20 CN claimed
CN-117088357-A Preparation method and application of nano porous carbon material with continuous structure 东南大学 2023-11-21 CN claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
US-RE30798-E BY REACTING 4-FLUORO-3-NITROANILINES WITH AMMONIA OR A PRIMARY OR SECONDARY AMINE CLAIROL INCORPORATED (US) 1981-11-17 US claimed
US-20250243188-A1 METHIONINE ADENOSYLTRANSERASE 2A INHIBITORS IDEAYA BIOSCIENCES, INC. 2025-07-31 US disclosed
US-20250177484-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll-Like Receptor (TLR) Agonist Prodrugs Useful in the Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2025-06-05 US disclosed
US-12311010-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor(“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN disclosed
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
WO-2025043967-A1 PREPARATION METHOD FOR AND USE OF NANOPOROUS CARBON MATERIAL HAVING CONTINUOUS STRUCTURE 东南大学 2025-03-06 WO disclosed
US-5587392-A THERAPY FOR ESTROGEN DEPENDENT DISEASES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1996-12-24 US disclosed
EP-0684235-A1 Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-11-29 EP disclosed
US-4857070-A 2,4-Diaminophenyl tetrahydrofurfuryl ethers, processes for their preparation and tinting compositions, which contain them for keratinic fibres SEIDEL WINFRIED (DE) 1989-08-15 US disclosed
EP-0000121-A1 6-(1-Piperazinyl)-quinoxaline, process for its preparation and pharmaceutical compositions thereof MERCK & CO. INC. (US) 1979-01-10 EP disclosed
US-4091101-A ANORECTIC AGENTS MERCK & CO., INC. (US) 1978-05-23 US disclosed
US-3959377-A FROM 4-FLUORO-3-NITROANILINE AND ANILINE CLAIROL INCORPORATED (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243188-A1 METHIONINE ADENOSYLTRANSERASE 2A INHIBITORS MAT2A, MAT2B, MAT1A TDP1 809/4885SMN1; SMN2 1209/4885PDE7A 852/4885
US-12311010-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor(“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR4, TLR7 TDP1 1458/4885SMN1; SMN2 2645/4885PDE7A 765/4885
US-20250177484-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll-Like Receptor (TLR) Agonist Prodrugs Useful in the Treatment of Cancer and Methods Thereof TLR1, TLR7, TLR4 TDP1 1004/4885SMN1; SMN2 2536/4885PDE7A 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.