SCHEMBL29655247

SCHEMBL29655247

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nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.60
PTPN1 P18031 2/20 0.51
BACE1 P56817 8/20 0.48
BACE2 Q9Y5Z0 2/20 0.48
NAALAD2 Q9Y3Q0 1/20 0.48
CTSD P07339 1/20 0.47
MME P08473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29606046 0.94 FOLH1 (0.60) FOLH1PTPN1BACE1BACE2NAALAD2
SCHEMBL30128626 0.94 FOLH1 (0.60) FOLH1PTPN1BACE1BACE2NAALAD2
SCHEMBL30436991 0.94 FOLH1 (0.60) FOLH1PTPN1BACE1BACE2NAALAD2
SCHEMBL1674773 0.94 FOLH1 (0.63) FOLH1PTPN1BACE1BACE2NAALAD2
SCHEMBL31410843 0.93 FOLH1 (0.58) FOLH1PTPN1BACE1BACE2NAALAD2
SCHEMBL31454946 0.93 FOLH1 (0.61) FOLH1BACE1BACE2NAALAD2CTSD
SCHEMBL30553676 0.93 FOLH1 (0.61) FOLH1BACE1BACE2NAALAD2CTSD
SCHEMBL29846196 0.93 FOLH1 (0.61) FOLH1BACE1BACE2NAALAD2CTSD
SCHEMBL29883705 0.92 FOLH1 (0.52) FOLH1PTPN1BACE1BACE2CTSD
SCHEMBL29400510 0.92 FOLH1 (0.63) FOLH1BACE1BACE2NAALAD2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027181-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2025-02-06 WO disclosed
EP-4388105-A1 PERSISTENT ALLOGENEIC MODIFIED IMMUNE CELLS AND METHODS OF USE THEREOF Beam Therapeutics Inc. (US) 2024-06-26 EP disclosed
US-20240117059-A1 THERAPEUTIC ANTIGEN-BINDING MOLECULE WITH A FcRn-BINDING DOMAIN THAT PROMOTES ANTIGEN CLEARANCE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-04-11 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
EP-4324850-A2 THERAPEUTIC ANTIGEN-BINDING MOLECULE WITH A FCRN-BINDING DOMAIN THAT PROMOTES ANTIGEN CLEARANCE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-21 EP disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
WO-2023023515-A1 PERSISTENT ALLOGENEIC MODIFIED IMMUNE CELLS AND METHODS OF USE THEREOF BEAM THERAPEUTICS INC. (US) 2023-02-23 WO disclosed
US-20220361545-A1 ENHANCED SALT COMPOSITIONS AND METHODS OF PREPARATION THEREOF DOUXMATOK LTD (IL) 2022-11-17 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885PTPN1 3282/4885BACE1 4303/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885PTPN1 3282/4885BACE1 4303/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FOLH1 1289/4885PTPN1 3282/4885BACE1 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.