SCHEMBL29655324

SCHEMBL29655324

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 16/20 0.61
NPY1R P25929 10/20 0.61
NPY5R Q15761 8/20 0.61
NPY2R P49146 6/20 0.61
ALDH1A1 P00352 1/20 0.41
KISS1R Q969F8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639946 1.00 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL29947104 1.00 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL30958046 0.97 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL29794924 0.97 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL3138312 0.97 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL3138301 0.97 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL29531992 0.97 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RALDH1A1
SCHEMBL30647286 0.96 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29947085 0.96 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31601685 0.96 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466974-A Antimicrobial peptide and application thereof 中国药科大学 2024-01-30 CN claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
CN-117466974-B Antimicrobial peptide and application thereof 中国药科大学 2024-03-26 CN disclosed
CN-117466974-A Antimicrobial peptide and application thereof 中国药科大学 2024-01-30 CN disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-109942714-B Functional polypeptide and application 中国药科大学 2022-07-08 CN disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 NPY4R 1026/4885NPY1R 920/4885NPY5R 1220/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 NPY4R 1026/4885NPY1R 920/4885NPY5R 1220/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 NPY4R 1026/4885NPY1R 920/4885NPY5R 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.