SCHEMBL29655436

SCHEMBL29655436

Brc1ccc2[nH]c3c(Br)cc(Br)cc3c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.54
PIM3 Q86V86 2/20 0.51
CHUK O15111 1/20 0.47
PIM1 P11309 2/20 0.46
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
MAPT P10636 2/20 0.43
CCNB2 O95067 1/20 0.43
CCNE2 O96020 1/20 0.43
CDK1 P06493 1/20 0.43
CDK4 P11802 1/20 0.43
CCNB1 P14635 1/20 0.43
CCND1 P24385 1/20 0.43
CCNE1 P24864 1/20 0.43
CDK2 P24941 1/20 0.43
CCNB3 Q8WWL7 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28520339 1.00 AR (0.54) ARPIM3CHUKPIM1LMNA
SCHEMBL25252971 0.82 ALDH1A1 (0.48) ARMAPTCCNB2CCNE2CDK1
SCHEMBL1298075 0.81 PIM3 (0.71) ARPIM3CHUKPIM1LMNA
SCHEMBL30972538 0.81 PIM3 (0.71) ARPIM3CHUKPIM1LMNA
SCHEMBL27917101 0.81 AR (0.51) ARPIM3CHUKPIM1LMNA
SCHEMBL30032842 0.81 AR (0.51) ARPIM3CHUKPIM1LMNA
SCHEMBL25223297 0.81 AR (0.70) ARPIM3CHUKPIM1LMNA
SCHEMBL27145752 0.81 AR (0.51) ARPIM3CHUKPIM1LMNA
SCHEMBL30972537 0.81 PIM3 (0.59) ARPIM3CHUKPIM1LMNA
SCHEMBL29366993 0.80 CHUK (0.64) ARPIM3CHUKPIM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN claimed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN claimed
CN-118883740-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in soil 舟山市食品药品检验检测研究院(国家海洋食品质量监督检验中心、浙江省海洋水产品质量检测中心、舟山市医疗器械质量监督检验所、舟山市药品不良反应监测中心、舟山市渔业检验检测中心、舟山市农产品质量检测中心) 2024-11-01 CN disclosed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN disclosed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN disclosed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN disclosed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN disclosed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN disclosed
CN-113620811-B Halogenation method of aromatic compound 中国科学院兰州化学物理研究所 2022-05-24 CN disclosed