SCHEMBL25252971

SCHEMBL25252971

Brc1cc(Br)c2[nH]c3ccccc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
AHR P35869 2/20 0.47
CCNE2 O96020 3/20 0.45
CDK4 P11802 3/20 0.45
CCND1 P24385 3/20 0.45
CCNE1 P24864 3/20 0.45
CDK2 P24941 3/20 0.45
CCNB2 O95067 2/20 0.45
CDK1 P06493 2/20 0.45
CCNB1 P14635 2/20 0.45
CCNB3 Q8WWL7 2/20 0.45
AR P10275 1/20 0.45
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28520339 0.82 AR (0.54) ALDH1A1HSD17B10CCNE2CDK4CCND1
SCHEMBL29655436 0.82 AR (0.54) ALDH1A1HSD17B10CCNE2CDK4CCND1
SCHEMBL28359835 0.81 AHR (0.48) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL28496358 0.81 ALDH1A1 (0.45) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL27447266 0.81 KIF11 (0.59) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL31518299 0.81 IDO1 (0.48) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL31188776 0.81 KIF11 (0.59) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL27290067 0.81 IDO1 (0.48) ALDH1A1GPR3HSD17B10AHRCCNE2
SCHEMBL22026631 0.80 AR (0.38) ALDH1A1AHRCCNE2CDK4CCND1
SCHEMBL14951418 0.79 HPGD (0.49) ALDH1A1GPR3HSD17B10AHRCCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-08-08 US disclosed
CN-114644638-B Nitrogen-containing heterocyclic compound and application thereof 广州华睿光电材料有限公司 2024-04-23 CN disclosed
CN-111087413-B Transition metal complex and organic electronic device thereof 广州华睿光电材料有限公司 2023-08-01 CN disclosed
US-20230189634-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189634-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
CN-116261384-A Light-emitting element and polycyclic compound for light-emitting element 三星显示有限公司 2023-06-13 CN disclosed
WO-2022127024-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF 广州华睿光电材料有限公司 2022-06-23 WO disclosed
CN-114644638-A Nitrogen-containing heterocyclic compound and application thereof 广州华睿光电材料有限公司 2022-06-21 CN disclosed
CN-113200992-B Nitrogen-containing compound, organic electroluminescent device, and electronic device 陕西莱特迈思光电材料有限公司 2022-05-20 CN disclosed
CN-113200992-A Nitrogen-containing compound, organic electroluminescent device, and electronic device 陕西莱特迈思光电材料有限公司 2021-08-03 CN disclosed
CN-111087413-A Transition metal complex and organic electronic device thereof 广州华睿光电材料有限公司 2020-05-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF NPR1, NPR3, NUCB2 ALDH1A1 2557/4885GPR3 569/4885HSD17B10 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.