SCHEMBL29655447

SCHEMBL29655447

Clc1ccc2[nH]c3c(Br)cc(Cl)cc3c2c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHUK O15111 2/20 0.45
RXFP1 Q9HBX9 2/20 0.44
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
CDC25A P30304 1/20 0.40
CDC25C P30307 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
MAP2 P11137 2/20 0.40
PTGS2 P35354 1/20 0.39
AR P10275 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PARP1 P09874 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28524076 1.00 CHUK (0.45) CHUKRXFP1LMNACYP1A2GAA
SCHEMBL23728950 0.86 LMNA (0.46) CHUKRXFP1LMNACYP1A2GAA
SCHEMBL31518299 0.84 IDO1 (0.48) CHUKMEN1KMT2A
SCHEMBL23702733 0.82 AR (0.49) CHUKRXFP1LMNACYP1A2GAA
SCHEMBL29805642 0.82 MET (0.39) CHUKGAAARKDM4E
SCHEMBL28796045 0.82 MET (0.39) CHUKGAAARKDM4E
SCHEMBL14292108 0.81 CHUK (0.57) CHUKRXFP1LMNACYP1A2GAA
SCHEMBL29655425 0.81 CHUK (0.57) CHUKRXFP1LMNACYP1A2GAA
SCHEMBL30981806 0.80 JAK2 (0.45) CHUKRXFP1LMNAMAP2PTGS2
SCHEMBL16433002 0.78 CHUK (0.52) CHUKRXFP1LMNACYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118243812-A Method for measuring carbazole compounds in aquatic products based on internal standard method 舟山市食品药品检验检测研究院(国家海洋食品质量监督检验中心、浙江省海洋水产品质量检测中心、舟山市医疗器械质量监督检验所、舟山市药品不良反应监测中心、舟山市渔业检验检测中心、舟山市农产品质量检测中心) 2024-06-25 CN claimed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN claimed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN claimed
CN-114814054-A Method for detecting 10 halogenated carbazole compounds in marine sediments 舟山市食品药品检验检测研究院 2022-07-29 CN claimed
CN-118937546-B Method for measuring carbazole and 9 halogenated carbazole in sediment by internal standard method 舟山市食品药品检验检测研究院 2025-02-07 CN disclosed
CN-118937546-A Method for measuring carbazole and 9 halogenated carbazole in sediment by internal standard method 舟山市食品药品检验检测研究院 2024-11-12 CN disclosed
CN-118883740-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in soil 舟山市食品药品检验检测研究院(国家海洋食品质量监督检验中心、浙江省海洋水产品质量检测中心、舟山市医疗器械质量监督检验所、舟山市药品不良反应监测中心、舟山市渔业检验检测中心、舟山市农产品质量检测中心) 2024-11-01 CN disclosed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN disclosed
CN-117092262-B Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2024-05-28 CN disclosed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN disclosed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN disclosed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN disclosed
CN-116144657-A Detection method of dioxin substances based on fish promoters 曲阜师范大学 2023-05-23 CN disclosed
CN-114814054-A Method for detecting 10 halogenated carbazole compounds in marine sediments 舟山市食品药品检验检测研究院 2022-07-29 CN disclosed
CN-113620811-B Halogenation method of aromatic compound 中国科学院兰州化学物理研究所 2022-05-24 CN disclosed