SCHEMBL420335

SCHEMBL420335

Brc1cccc2[nH]c3ccccc3c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.59
IMPDH1 P20839 1/20 0.59
CDK4 P11802 4/20 0.57
CCND1 P24385 4/20 0.57
CCNE2 O96020 2/20 0.57
CCNE1 P24864 2/20 0.57
CDK2 P24941 2/20 0.57
CAMK2B Q13554 2/20 0.57
CAMK2G Q13555 2/20 0.57
CAMK2D Q13557 2/20 0.57
CAMK2A Q9UQM7 2/20 0.57
CCNB2 O95067 1/20 0.57
CDK1 P06493 1/20 0.57
CCNB1 P14635 1/20 0.57
PRKACA P17612 1/20 0.57
PRKACG P22612 1/20 0.57
PRKACB P22694 1/20 0.57
CCNB3 Q8WWL7 1/20 0.57
ALDH1A1 P00352 2/20 0.54
GPR3 P46089 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724222 1.00 IMPDH2 (0.59) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL31259489 0.98 IMPDH2 (0.57) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL20071605 0.85 CDK4 (0.49) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL29655513 0.85 CDK4 (0.49) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL902312 0.84 ALDH1A1 (0.61) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL1344641 0.84 IMPDH2 (0.52) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL17433192 0.84 GABRP (0.55) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL30439700 0.84 FEN1 (0.52) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL6008314 0.84 FEN1 (0.52) IMPDH2IMPDH1CDK4CCND1CCNE2
SCHEMBL19567848 0.81 CDK4 (0.46) IMPDH2IMPDH1CDK4CCND1CCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462972-A Preparation method of cellulose-based long afterglow material 湖南工业大学 2025-02-18 CN claimed
CN-118834157-A Preparation method of total deuterated 4-bromocarbazole 上海亚兴生物医药科技有限公司 2024-10-25 CN claimed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN claimed
EP-4025643-B1 THERMOPLASTIC MOLDING COMPOSITIONS THAT RESIST HEAT BASF SE (DE) 2023-08-16 EP claimed
US-20220315738-A1 THERMOPLASTIC MOLDING COMPOSITIONS THAT RESIST HEAT BASF SE (DE) 2022-10-06 US claimed
CN-111518134-B Dynamic resonance aggregation-induced emission material for explosive detection and preparation method and application thereof 南京邮电大学 2022-05-17 CN claimed
CN-114341266-A Heat-resistant thermoplastic moulding materials 巴斯夫欧洲公司 2022-04-12 CN claimed
CN-109232383-B Method for synthesizing 4-bromocarbazole 河南省科学院高新技术研究中心 2022-02-01 CN claimed
CN-111960989-B Preparation method of 4-bromocarbazole 中钢集团南京新材料研究院有限公司 2021-11-02 CN claimed
CN-109232380-B Synthetic method of 4-bromocarbazole 新乡市润宇新材料科技有限公司 2021-08-10 CN claimed
CN-112010798-A Method for synthesizing N-arylcarbazole compound by catalyzing reaction of carbazole and arylhydrazine with transition metal 新乡市润宇新材料科技有限公司 2020-12-01 CN claimed
CN-111960989-A Preparation method of 4-bromocarbazole 中钢集团南京新材料研究院有限公司 2020-11-20 CN claimed
CN-111518134-A Dynamic resonance aggregation-induced emission material for explosive detection and preparation method and application thereof 南京邮电大学 2020-08-11 CN claimed
CN-107235891-B Preparation method of 4-bromocarbazole 北京八亿时空液晶科技股份有限公司 2020-02-21 CN claimed
CN-110305058-A A kind of 4- bromine carbazole preparation method 安徽秀朗新材料科技有限公司 2019-10-08 CN claimed
CN-109651232-A The method for preparing 4- bromine carbazole and its derivative 河北华清光电材料有限公司 2019-04-19 CN claimed
CN-109232380-A A kind of synthetic method of 4- bromine carbazole 新乡市润宇新材料科技有限公司 2019-01-18 CN claimed
CN-109232383-A A method of synthesis 4- bromine carbazole 河南省科学院高新技术研究中心 2019-01-18 CN claimed
CN-103936656-B A kind of preparation method of 4-bromine carbazole Henan Academy of SciencesChemistry Institute Co., Ltd. (CN) 2015-11-18 CN claimed
CN-103936656-A Preparation method of 4-bromocarbazole INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2014-07-23 CN claimed