Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.42 |
| ▸ | ADAM9 | Q13443 | 3/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611516 | 1.00 | CHEK1 (0.45) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL29177033 | 0.84 | CHEK1 (0.47) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL12992250 | 0.83 | CHEK1 (0.46) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL13545530 | 0.83 | CHEK1 (0.46) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL21700187 | 0.82 | NOTUM (0.47) | CHEK1JAK2MMP3ACEPOLB | |
| SCHEMBL12878828 | 0.81 | CHEK1 (0.45) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL15704266 | 0.81 | CHEK1 (0.48) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL15704265 | 0.81 | CHEK1 (0.48) | CHEK1JAK2MMP2ANPEPMMP9 | |
| SCHEMBL11395371 | 0.80 | NR1D1 (0.48) | CHEK1JAK2MMP2ANPEPNR1D1 | |
| SCHEMBL11395379 | 0.80 | NR1D1 (0.48) | CHEK1JAK2MMP2ANPEPNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979647-B | Azaindole derivative containing azaamino acid, preparation and application | 浙江大学 | 2022-05-20 | — | — | CN | disclosed |