Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648393 | 1.00 | THRB (0.50) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL28650933 | 0.86 | THRB (0.49) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL2923609 | 0.85 | ALDH1A1 (0.50) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL28648734 | 0.85 | THRB (0.48) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL4434009 | 0.84 | GRN (0.51) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL19750003 | 0.84 | SCN9A (0.46) | POLBSCN9AALDH1A1LMNAMAPT | |
| SCHEMBL19750044 | 0.83 | ALDH1A1 (0.45) | POLBSCN9AALDH1A1LMNAMAPT | |
| SCHEMBL28782971 | 0.82 | SMN1; SMN2 (0.46) | THRBPOLBALDH1A1ELANELMNA | |
| SCHEMBL28782978 | 0.81 | SCN9A (0.48) | THRBPOLBSCN9AALDH1A1ELANE | |
| SCHEMBL28782980 | 0.81 | THRB (0.45) | THRBPOLBSCN9AALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621145-A | Diphenylamide derivatives of fluorophenyl and trifluoroethoxy pyrazole, and preparation method and application thereof | 南开大学 | 2022-06-14 | — | — | CN | disclosed |