SCHEMBL29655695

SCHEMBL29655695

NC(=O)CC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 5/20 0.51
▸ OPRM1 P35372 2/20 0.49
▸ OPRD1 P41143 2/20 0.49
▸ OPRK1 P41145 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574265 0.90 C5AR1 (0.56) F2OPRM1OPRD1
SCHEMBL29390515 0.90 OPRM1 (0.52) F2OPRM1OPRD1OPRK1
SCHEMBL29794087 0.87 F2 (0.58) F2OPRM1OPRD1
SCHEMBL29655724 0.86 F2 (0.60) F2
SCHEMBL30350823 0.86 APLNR (0.47) F2
SCHEMBL29590405 0.85 F2 (0.46) F2OPRM1OPRD1OPRK1
SCHEMBL30272533 0.85 F2 (0.56) F2
SCHEMBL29630549 0.85 F2 (0.45) F2OPRM1OPRD1OPRK1
SCHEMBL29531965 0.83 SLC6A2 (0.50) F2OPRM1OPRD1OPRK1
SCHEMBL29568748 0.83 APLNR (0.41) F2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4334341-A2 METHODS FOR STIMULATING AND TRANSDUCING T CELLS Juno Therapeutics GmbH (DE) 2024-03-13 — — EP disclosed
EP-4240756-A1 CELLS EXPRESSING A CHIMERIC RECEPTOR FROM A MODIFIED INVARIANT CD3 IMMUNOGLOBULIN SUPERFAMILY CHAIN LOCUS AND RELATED POLYNUCLEOTIDES AND METHODS Juno Therapeutics, Inc. (US) 2023-09-13 — — EP disclosed
EP-4150057-A2 PROCESS FOR PRODUCING DONOR-BATCHED CELLS EXPRESSING A RECOMBINANT RECEPTOR Juno Therapeutics, Inc. (US) 2023-03-22 — — EP disclosed
WO-2022234009-A2 METHODS FOR STIMULATING AND TRANSDUCING T CELLS JUNO THERAPEUTICS GMBH (DE) 2022-11-10 — — WO disclosed
WO-2022098787-A1 CELLS EXPRESSING A CHIMERIC RECEPTOR FROM A MODIFIED INVARIANT CD3 IMMUNOGLOBULIN SUPERFAMILY CHAIN LOCUS AND RELATED POLYNUCLEOTIDES AND METHODS JUNO THERAPEUTICS, INC. (US) 2022-05-12 — — WO disclosed
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