Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685996 | 1.00 | TRPV1 (0.60) | TRPV1POLBEPHX2 | |
| SCHEMBL23645891 | 0.89 | — | — | |
| SCHEMBL22660108 | 0.85 | POLB (0.56) | TRPV1POLBEPHX2 | |
| SCHEMBL23645905 | 0.82 | TRPV1 (0.57) | TRPV1POLBEPHX2 | |
| SCHEMBL22686740 | 0.82 | EPHX2 (0.48) | TRPV1POLBEPHX2 | |
| SCHEMBL22685998 | 0.82 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL22687375 | 0.82 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL29655850 | 0.82 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL22686123 | 0.80 | EPHX2 (0.50) | TRPV1EPHX2 | |
| SCHEMBL22687455 | 0.80 | EPHX2 (0.50) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213074-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213074-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | ABHD12, SAMHD1, ABHD11 | TRPV1 4789/4885POLB 919/4885EPHX2 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.