SCHEMBL29655801

CSCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CTSL	P07711	3/20	0.44

▸	CTSS	P25774	3/20	0.44

▸	CTSK	P43235	3/20	0.44

▸	CTSH	P09668	1/20	0.44

▸	APLNR	P35414	2/20	0.43

▸	FNTA	P49354	11/20	0.41

▸	FNTB	P49356	11/20	0.41

▸	PGGT1B	P53609	11/20	0.41

▸	KEAP1	Q14145	1/20	0.39

▸	GLP1R	P43220	1/20	0.38

▸	SCTR	P47872	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29655666	0.93	CTSL (0.46)	CTSLCTSSCTSKCTSHAPLNR
SCHEMBL31157744	0.90	CTSL (0.46)	CTSLCTSSCTSKCTSHAPLNR
SCHEMBL29380560	0.90	NPY4R (0.41)	CTSLCTSSCTSKCTSHGLP1R
SCHEMBL29721861	0.89	APLNR (0.44)	CTSLCTSSCTSKCTSHAPLNR
SCHEMBL31257005	0.88	FNTA (0.44)	APLNRFNTAFNTBPGGT1B
SCHEMBL31256962	0.88	NPY4R (0.49)	APLNRFNTAFNTBPGGT1B
SCHEMBL31157718	0.87	CTSL (0.48)	CTSLCTSSCTSKCTSHAPLNR
SCHEMBL31256998	0.87	NPY4R (0.42)	APLNRGLP1RSCTR
SCHEMBL31467530	0.86	NPY4R (0.41)	CTSLCTSSCTSKCTSHAPLNR
SCHEMBL29630666	0.86	GLP1R (0.41)	APLNRGLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4021414-A1	DRUG CONTAINING TARGETING LIPOSOMES	Nextar Chempharma Solutions Ltd. (IL)	2022-07-06	—	—	EP	disclosed