Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798577 | 1.00 | POLB (0.45) | POLBTDP1NNMTALDH1A1KDM4E | |
| SCHEMBL28798635 | 0.88 | TDP1 (0.57) | POLBTDP1NNMTALDH1A1KDM4E | |
| SCHEMBL29656519 | 0.88 | TDP1 (0.57) | POLBTDP1NNMTALDH1A1KDM4E | |
| SCHEMBL21875463 | 0.83 | MAPT (0.39) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL30521061 | 0.83 | MAPT (0.39) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL2576373 | 0.82 | POLB (0.49) | POLBTDP1NNMTALDH1A1KDM4E | |
| SCHEMBL29656623 | 0.81 | TUBB4A (0.47) | ALDH1A1KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL28798591 | 0.81 | TUBB4A (0.47) | ALDH1A1KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL29656731 | 0.79 | TUBB4A (0.50) | ALDH1A1KMT2ARAB9ANPC1MAPK8 | |
| SCHEMBL23797063 | 0.77 | NNMT (0.53) | POLBTDP1NNMTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539245-A | Pyrimidine-fused ring derivative-containing regulator, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |