SCHEMBL29657170

SCHEMBL29657170

CC[C@@H](C)c1ccc(SC)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 12/20 0.61
ALDH1A1 P00352 2/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAOA P21397 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20025698 1.00 SLC6A4 (0.61) SLC6A4ALDH1A1USP2GAAPKM
SCHEMBL943047 0.84 ALDH1A1 (0.47) SLC6A4ALDH1A1USP2GAAPKM
SCHEMBL20621635 0.83 SLC6A4 (0.52) SLC6A4MAOASLC6A2SLC6A3
SCHEMBL598140 0.83 ALDH1A1 (0.52) ALDH1A1USP2GAAPKMHPGD
SCHEMBL24032674 0.80 SLC6A4 (0.48) SLC6A4ALDH1A1MAOASLC6A2SLC6A3
SCHEMBL1104208 0.80 SLC6A4 (0.50) SLC6A4ALDH1A1USP2GAAPKM
SCHEMBL2021510 0.80 ALDH1A1 (0.44) SLC6A4ALDH1A1USP2GAAPKM
SCHEMBL12201107 0.80 ALDH1A1 (0.44) SLC6A4ALDH1A1USP2GAAPKM
SCHEMBL20032404 0.79 SLC6A4 (0.63) SLC6A4MAOASLC6A2SLC6A3
SCHEMBL23516454 0.78 SLC6A4 (0.47) SLC6A4ALDH1A1MAOASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851479-B Method for preparing chiral alkyl compound by catalyzing asymmetric hydrogenation reaction of olefin with iron complex catalyst 浙江大学 2022-05-13 CN disclosed