Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657170 | 1.00 | SLC6A4 (0.61) | SLC6A4ALDH1A1USP2GAAPKM | |
| SCHEMBL943047 | 0.84 | ALDH1A1 (0.47) | SLC6A4ALDH1A1USP2GAAPKM | |
| SCHEMBL20621635 | 0.83 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL598140 | 0.83 | ALDH1A1 (0.52) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL24032674 | 0.80 | SLC6A4 (0.48) | SLC6A4ALDH1A1MAOASLC6A2SLC6A3 | |
| SCHEMBL1104208 | 0.80 | SLC6A4 (0.50) | SLC6A4ALDH1A1USP2GAAPKM | |
| SCHEMBL2021510 | 0.80 | ALDH1A1 (0.44) | SLC6A4ALDH1A1USP2GAAPKM | |
| SCHEMBL12201107 | 0.80 | ALDH1A1 (0.44) | SLC6A4ALDH1A1USP2GAAPKM | |
| SCHEMBL20032404 | 0.79 | SLC6A4 (0.63) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL23516454 | 0.78 | SLC6A4 (0.47) | SLC6A4ALDH1A1MAOASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-B1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | UNIV BERN (CH) | 2022-01-19 | — | — | EP | disclosed |
| US-10791739-B2 | Binary compositions as disruptors of orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2020-10-06 | — | — | US | disclosed |
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | VANDERBILT UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | OR51E2, OR10J3, ORC3 | SLC6A4 3622/4885ALDH1A1 2668/4885USP2 2409/4885 |
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | GFPT1, QPCT, GLB1 | SLC6A4 2747/4885ALDH1A1 3234/4885USP2 2020/4885 |
| US-10791739-B2 | Binary compositions as disruptors of orco-mediated odorant sensing | OR51E2, OR10J3, ORC3 | SLC6A4 3622/4885ALDH1A1 2668/4885USP2 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.