Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.69 |
| ▸ | RAB9A | P51151 | 11/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | NPC1 | O15118 | 10/20 | 0.69 |
| ▸ | GAA | P10253 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664358 | 0.88 | MAPT (0.69) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL23176467 | 0.86 | MAPT (0.55) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL17265012 | 0.83 | MAPT (0.57) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL29478092 | 0.83 | MAPT (0.71) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL25327971 | 0.83 | MAPT (0.71) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL914476 | 0.82 | KDM4E (1.00) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL29437945 | 0.82 | KDM4E (1.00) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL25329016 | 0.81 | MAPT (0.69) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL30211740 | 0.81 | MAPT (0.69) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL15426366 | 0.81 | MAPT (0.54) | MAPTRAB9AKDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239431-B | Method for preparing 2-benzothiazole substituted aniline compound by catalysis of copper compound | 广州大学 | 2022-05-13 | — | — | CN | disclosed |