SCHEMBL29657237

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nearest known ligand 0.49

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	CAPN1	P07384	2/20	0.46

▸	TASP1	Q9H6P5	1/20	0.46

▸	EP300	Q09472	1/20	0.44

▸	HIF1A	Q16665	1/20	0.44

▸	AGTR1	P30556	1/20	0.43

▸	AGTR2	P50052	1/20	0.43

▸	NTSR2	O95665	1/20	0.43

▸	NTSR1	P30989	1/20	0.43

▸	TGM2	P21980	1/20	0.43

▸	NPY2R	P49146	6/20	0.42

▸	NPY4R	P50391	6/20	0.42

▸	NPY5R	Q15761	6/20	0.42

▸	NPY1R	P25929	4/20	0.42

▸	CALCR	P30988	4/20	0.42

▸	CTSD	P07339	1/20	0.42

▸	CTSE	P14091	1/20	0.42

▸	CALCRL	Q16602	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31688339	0.92	CAPN1 (0.51)	CAPN1EP300HIF1AAGTR1AGTR2
SCHEMBL29575516	0.88	TGM2 (0.42)	CAPN1AGTR1AGTR2NTSR2NTSR1
SCHEMBL31688350	0.87	CALCR (0.50)	CAPN1EP300HIF1AAGTR1AGTR2
SCHEMBL10428029	0.86	KEAP1 (0.47)	CAPN1CTSDCALCRL
SCHEMBL29430190	0.86	CALCR (0.49)	CAPN1EP300HIF1ANTSR2NTSR1
SCHEMBL31182928	0.85	CAPN1 (0.51)	CAPN1EP300HIF1ANTSR2NTSR1
SCHEMBL31462021	0.84	EP300 (0.50)	CAPN1EP300HIF1ANPY2RNPY4R
SCHEMBL29839435	0.84	ACE (0.44)	TASP1AGTR1AGTR2NTSR2NTSR1
SCHEMBL31316151	0.83	F2R (0.43)	AGTR1AGTR2NTSR2NTSR1TGM2
SCHEMBL31462096	0.83	EP300 (0.49)	EP300HIF1ANTSR2NTSR1NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11359223-B2	Expression sequences	LONZA LTD (CH)	2022-06-14	—	—	US	disclosed