Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ILK | Q13418 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510736 | 1.00 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2138149 | 0.87 | KDM4E (0.66) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27750783 | 0.85 | KDM4E (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL13806292 | 0.81 | APP (0.55) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL231307 | 0.79 | KDM4E (0.75) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL29437945 | 0.78 | KDM4E (1.00) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL914476 | 0.78 | KDM4E (1.00) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27270305 | 0.78 | MAPT (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12854008 | 0.77 | KDM4E (0.72) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4593570 | 0.77 | KDM4E (0.65) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239431-B | Method for preparing 2-benzothiazole substituted aniline compound by catalysis of copper compound | 广州大学 | 2022-05-13 | — | — | CN | disclosed |