Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | NPC1 | O15118 | 9/20 | 0.66 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ILK | Q13418 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231307 | 0.88 | KDM4E (0.75) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28510736 | 0.87 | NPC1 (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29657261 | 0.87 | NPC1 (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12854008 | 0.86 | KDM4E (0.72) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL17180047 | 0.83 | KDM4E (0.57) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4593570 | 0.82 | KDM4E (0.65) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11645498 | 0.81 | NPC1 (0.47) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL827403 | 0.81 | RAB9A (0.67) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29528497 | 0.80 | NPC1 (0.56) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL19149022 | 0.80 | MAPT (0.59) | KDM4ENPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101368094-A | Yellow electrophosphorescent iridium complex, preparation method and uses thereof | CHANGCHUN OPTICS FINE MECH (CN) | 2009-02-18 | — | — | CN | claimed |
| EP-0721336-B1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RES CAMPAIGN TECH (GB) | 1999-07-14 | — | — | EP | claimed |
| EP-0721336-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-07-17 | — | — | EP | claimed |
| WO-1995006469-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-03-09 | — | — | WO | claimed |
| US-11384060-B2 | Amide compounds and use thereof | ALPHALA CO., LTD. (TW) | 2022-07-12 | — | — | US | disclosed |
| US-20190337915-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2019-11-07 | — | — | US | disclosed |
| CN-109338402-A | A kind of method of electro-catalysis benzo thioamide analog compound synthesis benzothiazole in water | 福建医科大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-109293599-A | A kind of method of microwave radiation benzo thioamide analog compound synthesis benzothiazole in water phase | 福建医科大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-106432132-A | Preparation method of 2-arylbenzothiazole compound | 西北师范大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-105777662-A | Benzoxazole and benzimidazole compounds and preparation method thereof | 信阳师范学院 | 2016-07-20 | — | — | CN | disclosed |
| CN-103951635-B | A kind of synthetic method being used as the thiazole compound of Neurology Department pharmaceutical intermediate | ZHONGXIN HOSPITAL, QINGDAO (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-103788013-B | Synthetic method of 2-aryl benzothiazole compounds | UNIV WENZHOU | 2015-07-01 | — | — | CN | disclosed |
| CN-1642879-A | Process for preparing diaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2005-07-20 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1487843-A2 | SUBSTITUTED PHENYLACETIC ACIDS | Metabolex, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040029933-A1 | Substituted phenylacetic acids | METABOLEX, INC. | 2004-02-12 | — | — | US | disclosed |
| WO-2003080545-A2 | SUBSTITUTED PHENYLACETIC ACIDS | METABOLEX, INC. (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-0721336-B1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RES CAMPAIGN TECH (GB) | 1999-07-14 | — | — | EP | disclosed |
| US-5874431-A | ANTITUMOR AGENTS; BREAST CANCER | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337915-A1 | AMIDE COMPOUNDS AND USE THEREOF | GLP1R, IAPP, GPR119 | KDM4E 2631/4885NPC1 1116/4885RAB9A 1229/4885 |
| US-20040029933-A1 | Substituted phenylacetic acids | PNLIP, PC, PAOX | KDM4E 3805/4885NPC1 305/4885RAB9A 2953/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | KDM4E 3428/4885NPC1 4102/4885RAB9A 2254/4885 |
| US-11384060-B2 | Amide compounds and use thereof | GLP1R, IAPP, GPR119 | KDM4E 2631/4885NPC1 1116/4885RAB9A 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.